How do we get a DALL-E or GPT-3 for science? If you’re in tech, showing a friend outputs from generative AI models like DALL-E or GPT-3 is like showing them magic. These tools represent the next generation of the web. They derive from the synthesis of massive amounts of information, beyond a simple linkage, to create tools with generative capacity. So how can we create a similarly magical experience in science, where anyone can ask a question of the scientific literature in plain language and get an understandable answer backed by evidence? How can we help researchers create, develop, refine, and test their hypotheses? How can we potentially avoid wasting billions of dollars on failing hypotheses in Alzheimer’s research and erroneous connections between genetics and depression?